Searchable abstracts of presentations at key conferences in endocrinology

ea0013oc19 | Novartis Basic Endocrinology Award | SFEBES2007

Steroidogenic gene transcription in the human hippocampus and cerebellum: a comprehensive survey

MacKenzie Scott , Dewar Deborah , Stewart William , Fraser Robert , Connell John , Davies Eleanor

Previous studies investigating steroidogenic enzymes in the brain have often focused on only a few genes at a time, using animal models or pooled human RNA to investigate their expression. For this study, we obtained RNA from individual archived human brain tissue samples in order to analyse the transcription of twelve genes involved with steroid biosynthesis and metabolism within the cerebellum and hippocampus.We developed realtime RT-PCR assays for twe...